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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 5' and Ligand = 'BDBM50194253'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 5


(Homo sapiens (Human))
BDBM50194253
PNG
(CHEMBL3946489)
Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7]\[#6](-[#7](-[#6])-[#6])=[#7+](/[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1 |r|
Show InChI InChI=1/C42H63N9O9/c1-27(2)23-32(40(58)47-31(38(56)49-34(26-52)41(59)60-8)21-15-16-22-43-42(50(4)5)51(6)7)48-36(54)28(3)45-39(57)33(24-29-17-11-9-12-18-29)46-35(53)25-44-37(55)30-19-13-10-14-20-30/h9-14,17-20,27-28,31-34,52H,15-16,21-26H2,1-8H3,(H6,44,45,46,47,48,49,53,54,55,56,57,58)/p+1/t28-,31-,32-,33-,34-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX5 chromodomain (18 to 75 residues) expressed in Escherichia coli Rosetta BL21(DE3)p...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
More data for this
Ligand-Target Pair