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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 7' and Ligand = 'BDBM50194458'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromobox protein homolog 7


(Homo sapiens (Human))		BDBM50194458
PNG
(CHEMBL3987134)
Show SMILES CCN(CC)CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(CN)cc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1S/C44H69N7O8/c1-10-51(11-2)23-13-12-14-34(40(55)50-37(27-52)43(58)59-9)47-42(57)35(24-28(3)4)48-38(53)29(5)46-41(56)36(25-30-15-17-31(26-45)18-16-30)49-39(54)32-19-21-33(22-20-32)44(6,7)8/h15-22,28-29,34-37,52H,10-14,23-27,45H2,1-9H3,(H,46,56)(H,47,57)(H,48,53)(H,49,54)(H,50,55)/t29-,34-,35-,36-,37-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...

J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair