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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 7' and Ligand = 'BDBM50194462'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromobox protein homolog 7


(Homo sapiens (Human))		BDBM50194462
PNG
(CHEMBL3898460)
Show SMILES CC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN(CC)CC)C(=O)N[C@@H](CO)C(=O)OC |r|
Show InChI InChI=1S/C44H68N6O8/c1-10-33(45-42(56)36(27-30-18-14-13-15-19-30)47-38(52)31-21-23-32(24-22-31)44(6,7)8)39(53)48-35(26-29(4)5)41(55)46-34(20-16-17-25-50(11-2)12-3)40(54)49-37(28-51)43(57)58-9/h13-15,18-19,21-24,29,33-37,51H,10-12,16-17,20,25-28H2,1-9H3,(H,45,56)(H,46,55)(H,47,52)(H,48,53)(H,49,54)/t33-,34-,35-,36-,37-/m0/s1
PDB

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PC cid
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Similars
Article
PubMed
n/an/a 240n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human C-terminal His-tagged CBX7 chromodomain (8 to 62 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...

J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair