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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 7 (CBX7)' and Ligand = 'BDBM50009512'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 7 (CBX7)


(Homo sapiens (Human))
BDBM50009512
PNG
(CHEMBL3234189)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(O)=O)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CO)C(N)=O |r|
Show InChI InChI=1S/C38H55N7O9/c1-23(2)20-29(37(52)41-28(14-10-11-19-45(4,5)6)35(50)44-31(22-46)32(39)47)42-33(48)24(3)40-36(51)30(21-25-12-8-7-9-13-25)43-34(49)26-15-17-27(18-16-26)38(53)54/h7-9,12-13,15-18,23-24,28-31,46H,10-11,14,19-22H2,1-6H3,(H7-,39,40,41,42,43,44,47,48,49,50,51,52,53,54)/p+1/t24-,28-,29-,30-,31-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.20E+3n/an/an/an/an/an/a



University of Victoria

Curated by ChEMBL


Assay Description
Displacement of FITC-labeled H3K27me3 from CBX7 (unknown origin) after 15 mins by fluorescence polarization assay


J Med Chem 57: 2874-83 (2014)


Article DOI: 10.1021/jm401487x
BindingDB Entry DOI: 10.7270/Q2571DJ3
More data for this
Ligand-Target Pair