new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 8' and Ligand = 'BDBM50194460'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 8


(Homo sapiens (Human))
BDBM50194460
PNG
(CHEMBL3942638)
Show SMILES CNC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)c1ccccc1 |r|
Show InChI InChI=1/C26H43N5O4/c1-18(2)17-22(30-23(32)19(3)28-24(33)20-13-9-8-10-14-20)26(35)29-21(25(34)27-4)15-11-12-16-31(5,6)7/h8-10,13-14,18-19,21-22H,11-12,15-17H2,1-7H3,(H3-,27,28,29,30,32,33,34,35)/p+1/t19-,21-,22-/s2
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.00E+4n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX8 chromodomain (8 to 61 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair