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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 8' and Ligand = 'BDBM50194466'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chromobox protein homolog 8


(Homo sapiens (Human))
BDBM50194466
PNG
(CHEMBL3958557)
Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)C(C)(C)C |r|
Show InChI InChI=1/C42H64N6O8/c1-27(2)24-33(40(54)44-32(18-14-15-23-48(7,8)9)38(52)47-35(26-49)41(55)56-10)45-36(50)28(3)43-39(53)34(25-29-16-12-11-13-17-29)46-37(51)30-19-21-31(22-20-30)42(4,5)6/h11-13,16-17,19-22,27-28,32-35,49H,14-15,18,23-26H2,1-10H3,(H4-,43,44,45,46,47,50,51,52,53,54)/p+1/t28-,32-,33-,34-,35-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His-tagged CBX8 chromodomain (8 to 61 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...


J Med Chem 59: 8913-8923 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00801
BindingDB Entry DOI: 10.7270/Q2H1340D
More data for this
Ligand-Target Pair