Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 8' and Ligand = 'BDBM50194467'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chromobox protein homolog 8 (Homo sapiens (Human))	BDBM50194467 (CHEMBL3918626) Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN(C)C1CNC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1 |r| Show InChI InChI=1S/C41H60N8O9/c1-26(2)20-32(40(56)46-31(38(54)48-34(25-50)41(57)58-5)18-12-13-19-49(4)30-22-42-23-30)47-36(52)27(3)44-39(55)33(21-28-14-8-6-9-15-28)45-35(51)24-43-37(53)29-16-10-7-11-17-29/h6-11,14-17,26-27,30-34,42,50H,12-13,18-25H2,1-5H3,(H,43,53)(H,44,55)(H,45,51)(H,46,56)(H,47,52)(H,48,54)/t27-,31-,32-,33-,34-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His-tagged CBX8 chromodomain (8 to 61 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...				J Med Chem 59: 8913-8923 (2016) Article DOI: 10.1021/acs.jmedchem.6b00801 BindingDB Entry DOI: 10.7270/Q2H1340D
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