Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromobox protein homolog 8' and Ligand = 'BDBM50194468'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chromobox protein homolog 8 (Homo sapiens (Human))	BDBM50194468 (CHEMBL3966329) Show SMILES COC(=O)[C@H](CO)NC(=O)[C@H](CCCCN1CCCCC1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)c1ccccc1 |r| Show InChI InChI=1S/C42H61N7O9/c1-28(2)24-33(41(56)46-32(39(54)48-35(27-50)42(57)58-4)20-12-15-23-49-21-13-7-14-22-49)47-37(52)29(3)44-40(55)34(25-30-16-8-5-9-17-30)45-36(51)26-43-38(53)31-18-10-6-11-19-31/h5-6,8-11,16-19,28-29,32-35,50H,7,12-15,20-27H2,1-4H3,(H,43,53)(H,44,55)(H,45,51)(H,46,56)(H,47,52)(H,48,54)/t29-,32-,33-,34-,35-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Antagonist activity at recombinant human N-terminal His-tagged CBX8 chromodomain (8 to 61 residues) expressed in Escherichia coli Rosetta BL21(DE3)pL...				J Med Chem 59: 8913-8923 (2016) Article DOI: 10.1021/acs.jmedchem.6b00801 BindingDB Entry DOI: 10.7270/Q2H1340D
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