Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50098843'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50098843 (2-{2-[2-(5-Amino-6-oxo-2-pyridin-4-yl-6H-pyrimidin...) Show SMILES COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1ccncc1 Show InChI InChI=1S/C29H24N6O6/c1-40-29(39)19-7-8-23-21(14-19)34-27(41-23)25(37)22(13-17-5-3-2-4-6-17)33-24(36)16-35-26(18-9-11-31-12-10-18)32-15-20(30)28(35)38/h2-12,14-15,22H,13,16,30H2,1H3,(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	43.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Inhibitory activity evaluated against chymase from human heart.				J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K
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