Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50098864'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50098864 (2-(2-{2-[5-Amino-2-(3-nitro-phenyl)-6-oxo-6H-pyrim...) Show SMILES COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C30H24N6O8/c1-43-30(40)19-10-11-24-22(14-19)34-28(44-24)26(38)23(12-17-6-3-2-4-7-17)33-25(37)16-35-27(32-15-21(31)29(35)39)18-8-5-9-20(13-18)36(41)42/h2-11,13-15,23H,12,16,31H2,1H3,(H,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	41.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Inhibitory activity evaluated against chymase from human heart.				J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K
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