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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50135506'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chymase


(Homo sapiens (Human))		BDBM50135506
PNG
(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Show SMILES Cc1c(sc2ccc(F)cc12)S(=O)(=O)Nc1ccc(CO)cc1S(C)(=O)=O
Show InChI InChI=1S/C17H16FNO5S3/c1-10-13-8-12(18)4-6-15(13)25-17(10)27(23,24)19-14-5-3-11(9-20)7-16(14)26(2,21)22/h3-8,19-20H,9H2,1-2H3
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MMDB

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Toa Eiyo Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against human chymase

Bioorg Med Chem Lett 13: 4085-8 (2003)


BindingDB Entry DOI: 10.7270/Q2QN665P
More data for this
Ligand-Target Pair