Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM12567 (2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2 | -49.7 | n/a | n/a | n/a | n/a | n/a | 7.8 | 25 |
GlaxoSmithKline | Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate... | Bioorg Med Chem Lett 16: 3784-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.053 BindingDB Entry DOI: 10.7270/Q2416V9V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM12567 (2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | D3R | n/a | n/a | 4.36 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description D3R246 | D3R 246: (2015) BindingDB Entry DOI: 10.7270/Q2BV7FGN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM12567 (2-[(6-chloronaphthalene-2-)[(3S)-1-[(2S)-1-(morpho...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | D3R | n/a | n/a | 14.3 | n/a | n/a | n/a | n/a | n/a | n/a |
D3R | Assay Description D3R245 | D3R 245: (2015) BindingDB Entry DOI: 10.7270/Q2GM865X | |||||||||||
More data for this Ligand-Target Pair |