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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM12768'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM12768
PNG
(N-[4-(1H-1,3-benzodiazol-1-yl)phenyl]-1-(3-carbami...)
Show SMILES NC(=N)c1cccc(c1)-n1nc(Cn2ccnc2)cc1C(=O)Nc1ccc(cc1)-n1cnc2ccccc12
Show InChI InChI=1S/C28H23N9O/c29-27(30)19-4-3-5-23(14-19)37-26(15-21(34-37)16-35-13-12-31-17-35)28(38)33-20-8-10-22(11-9-20)36-18-32-24-6-1-2-7-25(24)36/h1-15,17-18H,16H2,(H3,29,30)(H,33,38)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
0.580 -52.2n/an/an/an/an/a7.022



Bristol-Myers Squibb Company



Assay Description
Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...


Bioorg Med Chem Lett 14: 5263-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.034
BindingDB Entry DOI: 10.7270/Q2TH8JX0
More data for this
Ligand-Target Pair