Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM13285'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13285 (3-Amino-5-[3-(S)-(7-methoxynaphthalen-2-ylsulfonyl...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cc(N)cc(c2)C(N)=N)C1=O |r| Show InChI InChI=1S/C23H25N5O4S/c1-32-19-4-2-15-3-5-20(12-16(15)11-19)33(30,31)27-21-6-7-28(23(21)29)13-14-8-17(22(25)26)10-18(24)9-14/h2-5,8-12,21,27H,6-7,13,24H2,1H3,(H3,25,26)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+3	-33.5	n/a	n/a	n/a	n/a	n/a	7.5	22
Rhone-Poulenc Rorer					Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...				J Med Chem 42: 3572-87 (1999) Article DOI: 10.1021/jm990041+ BindingDB Entry DOI: 10.7270/Q2KW5D9R
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM13285 (3-Amino-5-[3-(S)-(7-methoxynaphthalen-2-ylsulfonyl...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cc(N)cc(c2)C(N)=N)C1=O |r| Show InChI InChI=1S/C23H25N5O4S/c1-32-19-4-2-15-3-5-20(12-16(15)11-19)33(30,31)27-21-6-7-28(23(21)29)13-14-8-17(22(25)26)10-18(24)9-14/h2-5,8-12,21,27H,6-7,13,24H2,1H3,(H3,25,26)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rheinische Friedrich-Wilhelms-Universita£t Curated by ChEMBL					Assay Description Inhibition of human factor 10a				J Med Chem 54: 2944-51 (2011) Article DOI: 10.1021/jm200026b BindingDB Entry DOI: 10.7270/Q2ZG6TGM
					More data for this Ligand-Target Pair