Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM13651'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13651 (3-Oxybenzamide 37 | 5-[2-(2,4-dichlorophenyl)ethox...) Show SMILES NC(=O)c1cc(OCCc2ccc(Cl)cc2Cl)cc(c1)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C27H28Cl2N4O3/c28-22-2-1-19(25(29)16-22)7-12-36-24-14-20(26(30)34)13-21(15-24)27(35)32-17-18-5-10-33(11-6-18)23-3-8-31-9-4-23/h1-4,8-9,13-16,18H,5-7,10-12,17H2,(H2,30,34)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM13651 (3-Oxybenzamide 37 | 5-[2-(2,4-dichlorophenyl)ethox...) Show SMILES NC(=O)c1cc(OCCc2ccc(Cl)cc2Cl)cc(c1)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C27H28Cl2N4O3/c28-22-2-1-19(25(29)16-22)7-12-36-24-14-20(26(30)34)13-21(15-24)27(35)32-17-18-5-10-33(11-6-18)23-3-8-31-9-4-23/h1-4,8-9,13-16,18H,5-7,10-12,17H2,(H2,30,34)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH Curated by ChEMBL					Assay Description Inhibitory activity against human Coagulation factor X				Bioorg Med Chem Lett 14: 2801-5 (2004) Article DOI: 10.1016/j.bmcl.2004.03.059 BindingDB Entry DOI: 10.7270/Q2XS5WW7
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM13651 (3-Oxybenzamide 37 | 5-[2-(2,4-dichlorophenyl)ethox...) Show SMILES NC(=O)c1cc(OCCc2ccc(Cl)cc2Cl)cc(c1)C(=O)NCC1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C27H28Cl2N4O3/c28-22-2-1-19(25(29)16-22)7-12-36-24-14-20(26(30)34)13-21(15-24)27(35)32-17-18-5-10-33(11-6-18)23-3-8-31-9-4-23/h1-4,8-9,13-16,18H,5-7,10-12,17H2,(H2,30,34)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...				Bioorg Med Chem Lett 28: 2343-2352 (2018) Article DOI: 10.1016/j.bmcl.2018.05.061 BindingDB Entry DOI: 10.7270/Q28918HM
					More data for this Ligand-Target Pair