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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM13872'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM13872
PNG
(1-[(3-carbamimidoylphenyl)methyl]-N-[(3-carbamoylp...)
Show SMILES NC(=N)c1cccc(Cn2c(cc3ccccc23)C(=O)NCc2cccc(c2)C(N)=O)c1
Show InChI InChI=1S/C25H23N5O2/c26-23(27)19-8-4-6-17(12-19)15-30-21-10-2-1-7-18(21)13-22(30)25(32)29-14-16-5-3-9-20(11-16)24(28)31/h1-13H,14-15H2,(H3,26,27)(H2,28,31)(H,29,32)
PDB
MMDB

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240n/an/an/an/an/an/an/an/a



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...


J Med Chem 45: 2749-69 (2002)


BindingDB Entry DOI: 10.7270/Q27H1GTW
More data for this
Ligand-Target Pair