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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM17110'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM17110
PNG
(3-[({[4-chloro-5-({4-chloro-2-[(5-chloropyridin-2-...)
Show SMILES COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)C(=O)NCCC(O)=O)c1Cl
Show InChI InChI=1S/C24H22Cl3N5O6S/c1-32(24(37)28-6-5-18(33)34)10-12-11-39-21(19(12)27)23(36)31-20-15(7-14(26)8-16(20)38-2)22(35)30-17-4-3-13(25)9-29-17/h3-4,7-9,11H,5-6,10H2,1-2H3,(H,28,37)(H,31,36)(H,33,34)(H,29,30,35)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
0.0220n/an/an/an/an/an/an/an/a



Berlex Biosciences



Assay Description
The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...


J Med Chem 50: 2967-80 (2007)


Article DOI: 10.1021/jm070125f
BindingDB Entry DOI: 10.7270/Q2J101F5
More data for this
Ligand-Target Pair