Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM294041 (US10106557, Compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.13 | n/a | n/a | n/a | n/a | n/a | n/a | 8.3 | n/a |
NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO., LTD. US Patent | Assay Description The inhibitory activity on coagulation factor Xa activity in human was measured by using Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl). A buffer of 50... | US Patent US10106557 (2018) BindingDB Entry DOI: 10.7270/Q2X63Q0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Rattus norvegicus (rat)) | BDBM294041 (US10106557, Compound 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 16.5 | n/a | n/a | n/a | n/a | n/a | n/a | 8.3 | n/a |
NORTH CHINA PHARMACEUTICAL NEW DRUG R&D CO., LTD. US Patent | Assay Description The inhibitory activity on coagulation factor Xa activity in rats was measured by using Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl). A buffer of 50 ... | US Patent US10106557 (2018) BindingDB Entry DOI: 10.7270/Q2X63Q0W | |||||||||||
More data for this Ligand-Target Pair |