Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50114478'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114478 (2-(3-Carbamimidoyl-phenoxy)-5-chloro-N-(2'-sulfamo...) Show SMILES NC(=N)c1cccc(Oc2ccc(Cl)cc2C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)c1 Show InChI InChI=1S/C26H21ClN4O4S/c27-18-10-13-23(35-20-5-3-4-17(14-20)25(28)29)22(15-18)26(32)31-19-11-8-16(9-12-19)21-6-1-2-7-24(21)36(30,33)34/h1-15H,(H3,28,29)(H,31,32)(H2,30,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
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