Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50114493'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50114493 (2-{2-[2-(1-Amino-isoquinolin-7-yloxy)-1-methyl-eth...) Show SMILES CC(COc1ccc2ccnc(N)c2c1)N1Cc2cc(ccc2C1=O)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C26H24N4O4S/c1-16(15-34-20-8-6-17-10-11-29-25(27)23(17)13-20)30-14-19-12-18(7-9-22(19)26(30)31)21-4-2-3-5-24(21)35(28,32)33/h2-13,16H,14-15H2,1H3,(H2,27,29)(H2,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Tested in vitro for the inhibitory activity against Coagulation factor Xa				Bioorg Med Chem Lett 12: 1657-61 (2002) BindingDB Entry DOI: 10.7270/Q2R49Q2T
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