Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50140433'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140433 (2-(3-Fluoro-naphthalen-2-yl)-5-trifluoromethyl-2H-...) Show SMILES Fc1cc(ccc1NC(=O)c1cc(nn1-c1cc2ccccc2cc1F)C(F)(F)F)C(=N)N1CCCCC1 Show InChI InChI=1S/C27H22F5N5O/c28-19-13-18(25(33)36-10-4-1-5-11-36)8-9-21(19)34-26(38)23-15-24(27(30,31)32)35-37(23)22-14-17-7-3-2-6-16(17)12-20(22)29/h2-3,6-9,12-15,33H,1,4-5,10-11H2,(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
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