Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50144127'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144127 (2-{4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-[4-...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCN(CC1)c1ccncc1)S(=O)(=O)c1cc2ccc(Cl)cc2s1 |c:4| Show InChI InChI=1S/C34H36ClN7O4S2/c1-38-13-12-37-33(38)24-2-4-25(5-3-24)34(44)42-19-18-41(48(45,46)32-20-26-6-7-27(35)21-30(26)47-32)23-29(42)22-31(43)40-16-14-39(15-17-40)28-8-10-36-11-9-28/h2-11,20-21,29H,12-19,22-23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
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