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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50358255'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50358255
PNG
(CHEMBL172511)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(OC)cc1NC(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C23H22N2O5/c1-28-17-8-4-15(5-9-17)22(26)24-20-13-12-19(30-3)14-21(20)25-23(27)16-6-10-18(29-2)11-7-16/h4-14H,1-3H3,(H,24,26)(H,25,27)
PDB
MMDB

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Article
PubMed
n/an/a 6.22E+3n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis


J Med Chem 54: 8051-65 (2011)


Article DOI: 10.1021/jm200868m
BindingDB Entry DOI: 10.7270/Q2D50ND9
More data for this
Ligand-Target Pair