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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50358261'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50358261
PNG
(CHEMBL1922230)
Show SMILES COc1ccc(cc1)C(=O)Nc1ccc(OC)cc1NC(=O)c1ccc(cc1)N1CCCN(C)CC1
Show InChI InChI=1S/C28H32N4O4/c1-31-15-4-16-32(18-17-31)22-9-5-20(6-10-22)28(34)30-26-19-24(36-3)13-14-25(26)29-27(33)21-7-11-23(35-2)12-8-21/h5-14,19H,4,15-18H2,1-3H3,(H,29,33)(H,30,34)
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 73.4n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis


J Med Chem 54: 8051-65 (2011)


Article DOI: 10.1021/jm200868m
BindingDB Entry DOI: 10.7270/Q2D50ND9
More data for this
Ligand-Target Pair