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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50358262'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50358262
PNG
(CHEMBL1922231)
Show SMILES COc1ccc(cc1)C(=O)Nc1cc(OC)ccc1NC(=O)c1ccc(cc1)N1CCCN(C)CC1
Show InChI InChI=1S/C28H32N4O4/c1-31-15-4-16-32(18-17-31)22-9-5-20(6-10-22)27(33)29-25-14-13-24(36-3)19-26(25)30-28(34)21-7-11-23(35-2)12-8-21/h5-14,19H,4,15-18H2,1-3H3,(H,29,33)(H,30,34)
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n/an/a 118n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis

J Med Chem 54: 8051-65 (2011)


Article DOI: 10.1021/jm200868m
BindingDB Entry DOI: 10.7270/Q2D50ND9
More data for this
Ligand-Target Pair