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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM50358271'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50358271
PNG
(CHEMBL1922338)
Show SMILES CN1CCCN(CC1)c1ccc(cc1)C(=O)Nc1c(O)cccc1NC(=O)c1ccc(F)cc1
Show InChI InChI=1S/C26H27FN4O3/c1-30-14-3-15-31(17-16-30)21-12-8-19(9-13-21)26(34)29-24-22(4-2-5-23(24)32)28-25(33)18-6-10-20(27)11-7-18/h2,4-13,32H,3,14-17H2,1H3,(H,28,33)(H,29,34)
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Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human factor 10A using chromogenic substrate S2222 by fluorometric analysis

J Med Chem 54: 8051-65 (2011)


Article DOI: 10.1021/jm200868m
BindingDB Entry DOI: 10.7270/Q2D50ND9
More data for this
Ligand-Target Pair