Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM81697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM81697 (4-Substituted Pyrrolidine Ring, 34) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(NC(=O)[C@H]2CC(O)CN2C(=O)Nc2ccc(Cl)cn2)c(F)c1 |r| Show InChI InChI=1S/C24H22ClFN4O5S/c1-36(34,35)21-5-3-2-4-17(21)14-6-8-19(18(26)10-14)28-23(32)20-11-16(31)13-30(20)24(33)29-22-9-7-15(25)12-27-22/h2-10,12,16,20,31H,11,13H2,1H3,(H,28,32)(H,27,29,33)/t16?,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development,					Assay Description FXa inhibition were determined by using an inhibition assay.				Chem Biol Drug Des 69: 444-50 (2007) Article DOI: 10.1111/j.1747-0285.2007.00520.x BindingDB Entry DOI: 10.7270/Q2PZ5799
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