Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM238264'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US10882855 (2021) BindingDB Entry DOI: 10.7270/Q2XG9V7Q
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd US Patent					Assay Description Inhibitory activities of compounds of the present invention against factor XIa, Xa, XIIa, IXa, VIIa, plasma kallikrein or thrombin were evaluated usi...				US Patent US10336741 (2019) BindingDB Entry DOI: 10.7270/Q2CR5WQP
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9585881 (2017) BindingDB Entry DOI: 10.7270/Q2D50Q0R
					More data for this Ligand-Target Pair