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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Collagenase' and Ligand = 'BDBM50127450'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Collagenase


(Homo sapiens (Human))
BDBM50127450
PNG
(CHEMBL51966 | N-Hydroxy-2-(7-hydroxy-1,1-dioxo-1,3...)
Show SMILES C[C@@H](N1CCNc2cc(O)ccc2S1(=O)=O)C(=O)NO
Show InChI InChI=1S/C11H15N3O5S/c1-7(11(16)13-17)14-5-4-12-9-6-8(15)2-3-10(9)20(14,18)19/h2-3,6-7,12,15,17H,4-5H2,1H3,(H,13,16)/t7-/m1/s1
PDB
MMDB

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100n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against broad spectrum matrix metalloprotease-9 (MMP-9)


J Med Chem 46: 1811-23 (2003)


Article DOI: 10.1021/jm020475w
BindingDB Entry DOI: 10.7270/Q2TQ60W7
More data for this
Ligand-Target Pair