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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin releasing factor receptor' and Ligand = 'BDBM50074439'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50074439
PNG
(1-(2-Bromo-4,6-dimethoxy-phenyl)-4,6-dimethyl-1H-p...)
Show SMILES COc1cc(Br)c(c(OC)c1)-n1ccc2c(C)cc(C)nc12 |(12.47,-15.06,;10.97,-14.75,;10.48,-13.3,;11.5,-12.14,;11.01,-10.69,;12.02,-9.53,;9.5,-10.37,;8.48,-11.53,;6.98,-11.21,;5.96,-12.35,;8.97,-12.98,;9.03,-8.92,;9.92,-7.66,;9.01,-6.42,;7.54,-6.91,;6.21,-6.14,;6.21,-4.6,;4.88,-6.91,;4.88,-8.45,;3.55,-9.22,;6.21,-9.22,;7.56,-8.45,)|
Show InChI InChI=1S/C17H17BrN2O2/c1-10-7-11(2)19-17-13(10)5-6-20(17)16-14(18)8-12(21-3)9-15(16)22-4/h5-9H,1-4H3
PDB
MMDB

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Article
PubMed
1n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity was determined against corticotropin releasing factor receptor 1


J Med Chem 42: 819-32 (1999)


Article DOI: 10.1021/jm980223o
BindingDB Entry DOI: 10.7270/Q22V2GT5
More data for this
Ligand-Target Pair