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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin releasing factor receptor 1' and Ligand = 'BDBM50074536'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50074536
PNG
((1-Ethyl-propyl)-[5-methyl-3-(2,4,6-trimethyl-phen...)
Show SMILES CCC(CC)Nc1nc(C)nc2n(nnc12)-c1c(C)cc(C)cc1C |(8.12,-1.07,;9.45,-1.84,;9.45,-3.39,;8.12,-4.16,;8.12,-5.7,;10.79,-4.16,;10.79,-5.7,;9.45,-6.47,;9.45,-8.01,;8.1,-8.78,;10.79,-8.78,;12.12,-8.01,;13.58,-8.48,;14.47,-7.23,;13.58,-6,;12.12,-6.47,;13.91,-9.99,;15.36,-10.46,;16.5,-9.43,;15.69,-11.95,;14.56,-13,;14.89,-14.5,;13.09,-12.51,;12.76,-11.02,;11.29,-10.55,)|
Show InChI InChI=1S/C19H26N6/c1-7-15(8-2)22-18-16-19(21-14(6)20-18)25(24-23-16)17-12(4)9-11(3)10-13(17)5/h9-10,15H,7-8H2,1-6H3,(H,20,21,22)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
5.70n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells


J Med Chem 42: 833-48 (1999)


Article DOI: 10.1021/jm980224g
BindingDB Entry DOI: 10.7270/Q2610ZGP
More data for this
Ligand-Target Pair