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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin releasing factor receptor 1' and Ligand = 'BDBM50116109'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50116109
PNG
(CHEMBL302742 | [3-(4-Chloro-2-methyl-phenyl)-2,5-d...)
Show SMILES CCCN(CCC)c1nc(C)nc2c(-c3ccc(Cl)cc3C)n(C)nc12 |(1.59,4.49,;.26,3.72,;.28,2.18,;-1.06,1.41,;-2.39,2.17,;-2.39,3.7,;-3.73,4.47,;-1.05,-.12,;-2.38,-.91,;-2.38,-2.45,;-3.72,-3.21,;-1.05,-3.21,;.29,-2.45,;1.76,-2.92,;2.24,-4.39,;1.2,-5.52,;1.68,-6.99,;3.18,-7.3,;3.66,-8.77,;4.2,-6.15,;3.74,-4.69,;4.75,-3.55,;2.66,-1.66,;4.2,-1.66,;1.76,-.4,;.29,-.89,)|
Show InChI InChI=1S/C20H26ClN5/c1-6-10-26(11-7-2)20-18-17(22-14(4)23-20)19(25(5)24-18)16-9-8-15(21)12-13(16)3/h8-9,12H,6-7,10-11H2,1-5H3
PDB
MMDB

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4n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cells


Bioorg Med Chem Lett 12: 2133-6 (2002)


BindingDB Entry DOI: 10.7270/Q2SQ8ZPK
More data for this
Ligand-Target Pair