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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-C' and Ligand = 'BDBM50154960'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-C


(Homo sapiens (Human))		BDBM50154960
PNG
(CHEMBL3775123)
Show SMILES Cn1ncc2cc(Cc3n[nH]c4ccc(cc34)C(=O)N3CC(O)C3)ccc12
Show InChI InChI=1S/C20H19N5O2/c1-24-19-5-2-12(6-14(19)9-21-24)7-18-16-8-13(3-4-17(16)22-23-18)20(27)25-10-15(26)11-25/h2-6,8-9,15,26H,7,10-11H2,1H3,(H,22,23)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Merck KGaA

Curated by ChEMBL


Assay Description
Displacement of dye-labeled ATP competitive probe from recombinant human CDK8/Cyclin C incubated for 20 mins by Alexa647 probe-based FRET assay

Bioorg Med Chem Lett 26: 1443-51 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.062
BindingDB Entry DOI: 10.7270/Q2NZ89G6
More data for this
Ligand-Target Pair