Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-C' and Ligand = 'BDBM50169079'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C (Homo sapiens (Human))	BDBM50169079 (CHEMBL3805857) Show SMILES NC(=O)c1ccc(Oc2cncc3sc(cc23)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C15H10N6O2S/c16-14(22)8-1-3-9(4-2-8)23-11-6-17-7-13-10(11)5-12(24-13)15-18-20-21-19-15/h1-7H,(H2,16,22)(H,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc Curated by ChEMBL					Assay Description Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assay				ACS Med Chem Lett 7: 223-8 (2016) Article DOI: 10.1021/acsmedchemlett.5b00278 BindingDB Entry DOI: 10.7270/Q29G5PPC
					More data for this Ligand-Target Pair