Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-T1' and Ligand = 'BDBM126475'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-T1 (Homo sapiens (Human))	BDBM126475 (US8778951, 285) Show SMILES COCCN[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2C[C@H](C)O[C@H](C)C2)n1 |r,wU:8.11,28.30,31.33,wD:5.4,(8.06,2.44,;6.52,2.44,;5.75,3.77,;4.21,3.77,;3.44,5.11,;1.9,5.11,;1.13,6.44,;-.41,6.44,;-1.18,5.11,;-.41,3.77,;1.13,3.77,;-2.72,5.11,;-4.06,4.34,;-4.06,2.8,;-5.39,2.03,;-6.72,2.8,;-8.06,2.03,;-6.72,4.34,;-5.39,5.11,;-5.39,.49,;-6.72,-.28,;-6.72,-1.82,;-5.39,-2.59,;-4.06,-1.82,;-2.72,-2.59,;-1.39,-1.82,;-.06,-2.59,;-.06,-4.13,;1.28,-4.9,;1.28,-6.44,;2.61,-4.13,;2.61,-2.59,;3.95,-1.82,;1.28,-1.82,;-4.06,-.28,)| Show InChI InChI=1S/C27H40ClN5O2/c1-18-13-20(14-19(2)35-18)16-30-26-6-4-5-25(33-26)23-15-27(31-17-24(23)28)32-22-9-7-21(8-10-22)29-11-12-34-3/h4-6,15,17-22,29H,7-14,16H2,1-3H3,(H,30,33)(H,31,32)/t18-,19+,20?,21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.00200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014) BindingDB Entry DOI: 10.7270/Q25B014T
					More data for this Ligand-Target Pair