Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-T1' and Ligand = 'BDBM126498'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-T1 (Homo sapiens (Human))	BDBM126498 (US8778951, 308) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1ccc(c(NCC2CCOCC2)n1)C(F)(F)F |r,wU:9.12,wD:6.5,3.3,(7.56,2.06,;6.23,2.83,;4.9,2.06,;3.56,2.83,;3.56,4.37,;2.23,2.06,;.89,2.83,;.89,4.37,;-.44,5.14,;-1.77,4.37,;-1.77,2.83,;-.44,2.06,;-3.11,5.14,;-4.44,4.37,;-4.44,2.83,;-5.77,2.06,;-7.11,2.83,;-8.44,2.06,;-7.11,4.37,;-5.77,5.14,;-5.77,.52,;-7.11,-.25,;-7.11,-1.79,;-5.77,-2.56,;-4.44,-1.79,;-3.11,-2.56,;-1.77,-1.79,;-.44,-2.56,;-.44,-4.1,;.89,-4.87,;2.23,-4.1,;2.23,-2.56,;.89,-1.79,;-4.44,-.25,;-5.77,-4.1,;-5.77,-5.64,;-4.23,-4.1,;-7.31,-4.1,)| Show InChI InChI=1S/C27H37ClF3N5O2/c1-17(16-37-2)34-19-3-5-20(6-4-19)35-25-13-21(23(28)15-32-25)24-8-7-22(27(29,30)31)26(36-24)33-14-18-9-11-38-12-10-18/h7-8,13,15,17-20,34H,3-6,9-12,14,16H2,1-2H3,(H,32,35)(H,33,36)/t17-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014) BindingDB Entry DOI: 10.7270/Q25B014T
					More data for this Ligand-Target Pair