Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-T1' and Ligand = 'BDBM126517'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-T1 (Homo sapiens (Human))	BDBM126517 (US8778951, 328) Show SMILES COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NC[C@H]2CCOC(C)(C)C2)n1 |r,wU:9.12,wD:27.28,6.5,3.3,(7.56,1.68,;6.23,2.45,;4.9,1.68,;3.56,2.45,;3.56,3.99,;2.23,1.68,;.89,2.45,;.89,3.99,;-.44,4.76,;-1.77,3.99,;-1.77,2.45,;-.44,1.68,;-3.11,4.76,;-4.44,3.99,;-4.44,2.45,;-5.77,1.68,;-7.11,2.45,;-8.44,1.68,;-7.11,3.99,;-5.77,4.76,;-5.77,.14,;-7.11,-.63,;-7.11,-2.17,;-5.77,-2.94,;-4.44,-2.17,;-3.11,-2.94,;-1.77,-2.17,;-.44,-2.94,;-.44,-4.48,;.89,-5.25,;2.23,-4.48,;2.23,-2.94,;3.56,-2.17,;2.23,-1.4,;.89,-2.17,;-4.44,-.63,)| Show InChI InChI=1S/C28H42ClN5O2/c1-19(18-35-4)32-21-8-10-22(11-9-21)33-27-14-23(24(29)17-31-27)25-6-5-7-26(34-25)30-16-20-12-13-36-28(2,3)15-20/h5-7,14,17,19-22,32H,8-13,15-16,18H2,1-4H3,(H,30,34)(H,31,33)/t19-,20+,21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.00100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Cdk9/cyclinT1 is purchased from Millipore, cat #14-685. The final total protein concentration in the assay 4 nM. The 5TAMRA-cdk7tide peptide substrat...				US Patent US8778951 (2014) BindingDB Entry DOI: 10.7270/Q25B014T
					More data for this Ligand-Target Pair