Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 1' and Ligand = 'BDBM2491'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM2491 (US8507510, 1.26) Show SMILES COc1cc(Nc2ncc(Br)c(N[C@H](C)[C@@H](C)O)n2)ccc1S(C)(=N)=O |r| Show InChI InChI=1S/C16H22BrN5O3S/c1-9(10(2)23)20-15-12(17)8-19-16(22-15)21-11-5-6-14(26(4,18)24)13(7-11)25-3/h5-10,18,23H,1-4H3,(H2,19,20,21,22)/t9-,10-,26?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description Kinase assay using either CDK1, CDK2 or VEGFR-2.				US Patent US8507510 (2013) BindingDB Entry DOI: 10.7270/Q2V69H76
					More data for this Ligand-Target Pair