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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 8' and Ligand = 'BDBM50189413'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 8


(Homo sapiens (Human))		BDBM50189413
PNG
(CHEMBL3827774)
Show SMILES CNC(=O)c1ccc2cncc(-c3ccc4n(C)ncc4c3)c2n1
Show InChI InChI=1S/C18H15N5O/c1-19-18(24)15-5-3-12-8-20-10-14(17(12)22-15)11-4-6-16-13(7-11)9-21-23(16)2/h3-10H,1-2H3,(H,19,24)
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Similars
Article
PubMed
n/an/a 3.40n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to CDK8 (unknown origin) expressed in human 7dF3 cells preincubated for 2 hrs followed by beta-oestradiol addition measured after 24...

ACS Med Chem Lett 7: 573-8 (2016)


Article DOI: 10.1021/acsmedchemlett.6b00022
BindingDB Entry DOI: 10.7270/Q2N87CRB
More data for this
Ligand-Target Pair