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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cyclooxygenase-2' and Ligand = 'BDBM50182339'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclooxygenase-2


(Canis familiaris)
BDBM50182339
PNG
(2-(furan-2-yl)-5-(1-(5-(methylsulfonyl)pyridin-2-y...)
Show SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccc(-c2ccco2)c(c1)C#N)C(F)(F)F
Show InChI InChI=1S/C21H13F3N4O3S/c1-32(29,30)15-5-7-20(26-12-15)28-17(10-19(27-28)21(22,23)24)13-4-6-16(14(9-13)11-25)18-3-2-8-31-18/h2-10,12H,1H3
PDB
MMDB

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Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Veterinary Medicine Research and Development Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of COX2 in canine whole blood


Bioorg Med Chem Lett 16: 2076-80 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.059
BindingDB Entry DOI: 10.7270/Q28K78PW
More data for this
Ligand-Target Pair