Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM50108517'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50108517 (CHEMBL3597843) Show SMILES CSc1cccc(Nc2nc(cs2)-c2ccc(F)cc2)c1 Show InChI InChI=1S/C16H13FN2S2/c1-20-14-4-2-3-13(9-14)18-16-19-15(10-21-16)11-5-7-12(17)8-6-11/h2-10H,1H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a
Istituto Giannina Gaslini Curated by ChEMBL					Assay Description Potentiator activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as increase in iodine influx measured after 30...				Eur J Med Chem 99: 14-35 (2015) Article DOI: 10.1016/j.ejmech.2015.05.030 BindingDB Entry DOI: 10.7270/Q25M67GT
					More data for this Ligand-Target Pair