Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator' and Ligand = 'BDBM50108523'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50108523 (CHEMBL3597889) Show SMILES CSc1cccc(Nc2nc(cs2)-c2sc(nc2C)-c2ccccc2)c1 Show InChI InChI=1S/C20H17N3S3/c1-13-18(26-19(21-13)14-7-4-3-5-8-14)17-12-25-20(23-17)22-15-9-6-10-16(11-15)24-2/h3-12H,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a
Istituto Giannina Gaslini Curated by ChEMBL					Assay Description Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells assessed as iodide influx after 24 hrs by HS-YFP assay				Eur J Med Chem 99: 14-35 (2015) Article DOI: 10.1016/j.ejmech.2015.05.030 BindingDB Entry DOI: 10.7270/Q25M67GT
					More data for this Ligand-Target Pair