Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM8916 (1-(2-Naphthyl)-1H-imidazole | 1-(naphthalen-2-yl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
UNIVERSITAT DES SAARLANDES US Patent | Assay Description V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per... | US Patent US9271963 (2016) BindingDB Entry DOI: 10.7270/Q2445KBN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM8916 (1-(2-Naphthyl)-1H-imidazole | 1-(naphthalen-2-yl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Saarland University | Assay Description The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro... | J Med Chem 48: 6632-42 (2005) Article DOI: 10.1021/jm0503704 BindingDB Entry DOI: 10.7270/Q2H41PNT | |||||||||||
More data for this Ligand-Target Pair |