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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome P450 144 (CYP144A1-TRV)' and Ligand = 'BDBM7886'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 144 (CYP144A1-TRV)


(Mycobacterium tuberculosis)
BDBM7886
PNG
(1-PIM | 1-phenyl-1H-imidazole | 1-phenylimidazole ...)
Show SMILES c1cn(cn1)-c1ccccc1
Show InChI InChI=1S/C9H8N2/c1-2-4-9(5-3-1)11-7-6-10-8-11/h1-8H
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PC cid
PC sid
PDB
UniChem

Patents

Article
PubMed
n/an/an/a 2.90E+5n/an/an/a7.0n/a



University of Cambridge



Assay Description
Optical titrations to determine the binding affinity (KD values) of ligands were carried out on a Cary 60 UV−visible spectrophotometer (Varian,...


Biochemistry 56: 1559-1572 (2017)


Article DOI: 10.1021/acs.biochem.6b00954
More data for this
Ligand-Target Pair