Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50073056 (4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human cytochrome P450 2C19 as S-mephenytoin-4-hydroxylation (100 uM) | J Med Chem 42: 202-5 (1999) Article DOI: 10.1021/jm980532e BindingDB Entry DOI: 10.7270/Q2PC31KS | |||||||||||
More data for this Ligand-Target Pair |