Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome b-245 heavy chain' and Ligand = 'BDBM244072'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome b-245 heavy chain (Homo sapiens (Human))	BDBM244072 (US9428478, TG6-181) Show SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)c1cc2cc(OC)c(OC)cc2[nH]1 Show InChI InChI=1S/C22H25N3O4/c1-27-17-6-4-16(5-7-17)24-8-10-25(11-9-24)22(26)19-12-15-13-20(28-2)21(29-3)14-18(15)23-19/h4-7,12-14,23H,8-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.00E+8	n/a	n/a	n/a	n/a	n/a	n/a
Emory University US Patent					Assay Description Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...				US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09
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