Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cytochrome b-245 heavy chain' and Ligand = 'BDBM244093'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome b-245 heavy chain (Homo sapiens (Human))	BDBM244093 (US9428478, TG6-254-1) Show SMILES COc1ccc(cc1F)N1CCN(CC1)C(=O)c1cc2cc(ccc2[nH]1)C(N)=O Show InChI InChI=1S/C21H21FN4O3/c1-29-19-5-3-15(12-16(19)22)25-6-8-26(9-7-25)21(28)18-11-14-10-13(20(23)27)2-4-17(14)24-18/h2-5,10-12,24H,6-9H2,1H3,(H2,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+9	n/a	n/a	n/a	n/a	n/a	n/a
Emory University US Patent					Assay Description Nox2 activity assay for primary screening: Plasma membranes were prepared from human neutrophils, which express large amounts of Nox2, stored at W...				US Patent US9428478 (2016) BindingDB Entry DOI: 10.7270/Q2RX9B09
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