Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM185678'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185678 (UNC10099984 | US9156822, 6) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-21-5-3-6-22(23(21)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-8-7-18-9-10-27-24(30)20(18)17-19/h3,5-8,17H,1-2,4,9-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.60	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185678 (UNC10099984 | US9156822, 6) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-21-5-3-6-22(23(21)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-8-7-18-9-10-27-24(30)20(18)17-19/h3,5-8,17H,1-2,4,9-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	6.20	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185678 (UNC10099984 | US9156822, 6) Show SMILES Clc1cccc(N2CCCN(CCCCOc3ccc4CCNC(=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C24H29Cl2N3O2/c25-21-5-3-6-22(23(21)26)29-13-4-12-28(14-15-29)11-1-2-16-31-19-8-7-18-9-10-27-24(30)20(18)17-19/h3,5-8,17H,1-2,4,9-16H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	9.87E+3	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair