Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM185679'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185679 (UNC10107953 | US9156822, 9) Show SMILES COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C25H33N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-9,11,19H,4-6,10,12-18H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185679 (UNC10107953 | US9156822, 9) Show SMILES COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C25H33N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-9,11,19H,4-6,10,12-18H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	4.60	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM185679 (UNC10107953 | US9156822, 9) Show SMILES COc1ccccc1N1CCCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C25H33N3O3/c1-30-24-8-3-2-7-23(24)28-15-6-14-27(16-17-28)13-4-5-18-31-21-11-9-20-10-12-25(29)26-22(20)19-21/h2-3,7-9,11,19H,4-6,10,12-18H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	163	n/a	n/a	7.4	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...				US Patent US9156822 (2015) BindingDB Entry DOI: 10.7270/Q2H41Q6D
					More data for this Ligand-Target Pair