Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50063280'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063280 (CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.19,-6.02,;10.03,-7.31,;11.57,-7.24,;12.41,-8.52,;13.95,-8.45,;14.64,-7.07,;13.8,-5.79,;12.27,-5.86,;16.18,-6.98,;17,-8.26,;18.54,-8.19,;19.23,-6.82,;18.38,-5.53,;16.86,-5.63,;7.67,-6.09,;6.83,-4.81,;5.3,-4.88,;4.59,-6.26,;5.43,-7.54,;6.97,-7.47,;3.05,-6.33,;2.21,-5.02,;.7,-5.11,;-.14,-3.81,;.56,-2.43,;2.1,-2.36,;2.94,-3.67,)| Show InChI InChI=1S/C21H30N6/c1-2-10-22-20(4-1)27-16-14-26(15-17-27)13-9-18-5-7-19(8-6-18)25-21-23-11-3-12-24-21/h1-4,10-12,18-19H,5-9,13-17H2,(H,23,24,25)/t18-,19-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063280 (CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...) Show SMILES C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:17.22,wD:14.15,(9.19,-6.02,;10.03,-7.31,;11.57,-7.24,;12.41,-8.52,;13.95,-8.45,;14.64,-7.07,;13.8,-5.79,;12.27,-5.86,;16.18,-6.98,;17,-8.26,;18.54,-8.19,;19.23,-6.82,;18.38,-5.53,;16.86,-5.63,;7.67,-6.09,;6.83,-4.81,;5.3,-4.88,;4.59,-6.26,;5.43,-7.54,;6.97,-7.47,;3.05,-6.33,;2.21,-5.02,;.7,-5.11,;-.14,-3.81,;.56,-2.43,;2.1,-2.36,;2.94,-3.67,)| Show InChI InChI=1S/C21H30N6/c1-2-10-22-20(4-1)27-16-14-26(15-17-27)13-9-18-5-7-19(8-6-18)25-21-23-11-3-12-24-21/h1-4,10-12,18-19H,5-9,13-17H2,(H,23,24,25)/t18-,19-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The in vitro intrinsic activity was measured at DA D2 receptor by measuring its ability to increase [3H]-thymidine uptake in CHO-K1 cells transfected...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair